Figure 7. Values for eta (Eta)(see Methods) for Cl of rHb1.1 determined from NONMEM's post hoc step are plotted against volunteers' ages, weights, heights, and dose of rHb1.1. Values for Cl were obtained from the optimal one-compartment model in which weight-normalized Cl varied as function of the predicted plasma concentration of rHb1.1. The thin line, determined using a smoother, suggests that the model in which Cl varies as a function (log) of the predicted plasma concentration of rHb1.1 explains most of the residual variability among volunteers.