Figure 2. Mean arterial plasma thromboxane B2levels (TxB2) in response to a bolus injection of 1.5 mg/kg rPF4 (given at time 0 min, open circles), or 2 mg/kg protamine (given at time 0 min, open squares) in heparinized sheep (2 mg/kg given at time -5 min), or 1.5 mg/kg rPF4 (given at time 0 min, filled circles) in lambs pretreated with 10 mg/kg indomethacin. Values are mean plus/minus SEM, n = 5. *P < 0.05 value differs from baseline.

Figure 2. Mean arterial plasma thromboxane B2levels (TxB2) in response to a bolus injection of 1.5 mg/kg rPF4 (given at time 0 min, open circles), or 2 mg/kg protamine (given at time 0 min, open squares) in heparinized sheep (2 mg/kg given at time -5 min), or 1.5 mg/kg rPF4 (given at time 0 min, filled circles) in lambs pretreated with 10 mg/kg indomethacin. Values are mean plus/minus SEM, n = 5. *P < 0.05 value differs from baseline.

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