Figure 5. (A) Effect of two levels of background PaCO2, on phrenic nerve activity (PNG) during the hyperoxic control period and during isocapnic hypoxia at 1 MAC halothane (protocol 2). O2(%), airway oxygen concentration. (B) Plot of peak phrenic activity (PPA) versus PaCO2(n = 4; protocol 2). There were no significant differences in the net PPA hypoxic responses for the two PaCO2levels.