Figure 6. Effect of intrathecal N-G-nitro-L-arginine methyl ester (L-Name) on punctate and nonpunctate hyperalgesia caused by an incision. (A, B) Withdrawal threshold after administration of 20 or 200 nmol of intrathecal L-Name on the day of surgery. The box and whisker plots are described in Figure 1. (C) Response frequency after incision in rats treated with 20 or 200 nmol intrathecally administered L-Name. The symbol represents the mean +/- SD.

Figure 6. Effect of intrathecal N-G-nitro-L-arginine methyl ester (L-Name) on punctate and nonpunctate hyperalgesia caused by an incision. (A, B) Withdrawal threshold after administration of 20 or 200 nmol of intrathecal L-Name on the day of surgery. The box and whisker plots are described in Figure 1. (C) Response frequency after incision in rats treated with 20 or 200 nmol intrathecally administered L-Name. The symbol represents the mean +/- SD.

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