Figure 5. (A) Effect of three levels of background PaCO2on phrenic nerve activity (PNG) during the hyperoxic control and carbon dioxide stimulation cycles (carbon dioxide bolus marker) at 1 MAC halothane. (B) Plot of peak phrenic nerve activity (PPA) versus PaCOsub 2 (n = 5; protocol 2). Filled circles: hyperoxic control PPA; open circles: PPA of the carbon dioxide bolus-stimulated breaths. There were no significant differences in the net phrenic responses to the carbon dioxide bolus for the three PaCO2levels.