Cerebral blood flow at various systemic blood flows in 10 patients during cardiopulmonary bypass. The four randomized flows are 1.0, 1.3, 1.6, and 2.0 l/min/m² and all at the same temperature, PaCO₂, and perfusion pressure. Reprinted with permission from Govier AV, Reves JG, McKay RD, Karp RB, Zorn GL, Morawetz RB, Smith LR, Adams M, Freeman AM: Factors and their influence on regional cerebral blood flow during nonpulsatile cardiopulmonary bypass. Ann Thorac Surg 1984; 38:592–600. Copyright © 1984 Elsevier.