Figure 3. Effect of antibodies against CYP1A2, 2C11, 2D1, and 3A2 on the catalytic activities of rat hepatic microsomes. The concentration of ropivacaine was 0.1 mM. The turnover rates of PPX, 4′-hydroxyropivacaine, and 3′-hydroxyropivacaine formed by rat hepatic microsomes without antibodies were 3.60, 0.038, and 0.400 nanomoles per minute per milligram of microsomal protein, respectively.