Figure 1. Mean serum inorganic fluoride ion concentrations during and after sevoflurane or isoflurane anesthesia. The sevoflurane^highgroup (n = 8) consisted of patients with a peak serum fluoride concentration in excess of 50 micro mol/l after sevoflurane anesthesia, and the sevoflurane sub low group (n = 15) consisted of patients whose peak fluoride concentrations were below 50 micro mol/l after sevoflurane anesthesia. The mean peak value in the sevoflurane^highgroup was 55.8 plus/minus 3.4 micro mol/l (1 h postanesthesia), in the sevoflurane^lowgroup 36.8 plus/minus 1.9 micro mol/l (at cessation of anesthesia), and in the isoflurane group (n = 11) 4.8 plus/minus 0.5 micro mol/l (16 h postanesthesia). Data points represent mean plus/minus SE.