Figure 2. Effect of subcutaneous (SC) morphine on nonpunctate mechanical hyperalgesia. A, Response frequency in saline- and morphine-treated animals (given at arrow) on the day of surgery. B, One day after surgery. C, Effect of SC morphine on withdrawal responses to pinprick. *P < 0.05 vs. 0 min by Friedman and Dunnett's test. (dagger)P < 0.05 vs. saline by Mann-Whitney rank sum test. The symbol represent the mean +/- SEM.