Figure 5. The halothane minimum alveolar concentration-sparing effect of dexmedetomidine after treatment with N-ethoxycarbonyl-2-ethoxy-1,2dibydroquinoline. In separate groups of rats, the minimum alveolar concentration for halothane was determined (A) 72 h after treatment with 0.3 mg *symbol* kg subcutaneous N-ethoxycarbonyl-2-ethoxy-1,2dihydroquinoline and (B) 24 h after treatment with 0.3 mg *symbol* kg subcutaneous N-ethoxy-carbonyl-2-ethoxy-1,2dibydroquinoline. The minimum alveolar concentration was determined twice in each animal, before and after administration of 30 micro gram *symbol* kg sup -1 intraperitoneal dexmedetomidine. Data are expressed as means plus/minus SEM. *P < 0.0001 compared with basal state (paired t test). n = 7 per group.