Figure 4. Changes in intracellular concentration of free Ca2+(indicated by F340/F380ratio) and muscle tension during contractions induced by caffeine (20 mM) without (A) or with 2.0% halothane (B, C)/4.5% isoflurane (D) during a Ca2+-freecondition. Caffeine (20 mM) was introduced alone (A), with 2.0% halothane (B) or 4.5% isoflurane (D) simultaneously and with the preincubation of 2.0% halothane (C).

Figure 4. Changes in intracellular concentration of free Ca2+(indicated by F340/F380ratio) and muscle tension during contractions induced by caffeine (20 mM) without (A) or with 2.0% halothane (B, C)/4.5% isoflurane (D) during a Ca2+-freecondition. Caffeine (20 mM) was introduced alone (A), with 2.0% halothane (B) or 4.5% isoflurane (D) simultaneously and with the preincubation of 2.0% halothane (C).

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