Figure 8. A comparison of the effects of thiopental on the N-methyl-D-aspartate (NMDA)-mediated increases in [Ca²⁺]ⁱin the pyramidal cell layer of hippocampal slices (Hippocampus) and layers II to III of cortical slices (Cortex). The difference between the hippocampus and cortex was analyzed using unpaired t test (NS = no significance), * P < 0.01 and ** P < 0.001 indicate significant differences from zero dose in hippocampus; and #P = 0.01 and ##P < 0.001 indicate significant differences from zero dose in the cortex, as calculated by analysis of variance followed by multiple comparisons with Dunnett's post hoc test (n = number of slices).