Figure 5. Comparison of the measured with the predicted concentrations during the infusion. The four graphs show the relationship of the normalized, corrected concentrations at 68, 76, 128, and 136 min to age. The line through the data is a linear least-squares fit. The asterisks represent the predicted normalized concentration for a 77-kg, 175-cm woman at ages 25, 50, and 75 yr. During the infusion, the concentrations tended to be higher in the elderly, whereas after the end of the infusion the opposite was observed. The full time course of the predicted concentrations after an infusion at 200 micro gram [center dot] kg-1[center dot] min-1is shown (bottom). The vertical lines represent the four time points chosen for the comparison above.