Figure 2. Changes with time in serum inorganic fluoride concentrations (top) and 24-h urinary fluoride excretion (bottom) in the three groups. Individual (open symbols) and mean +/- standard deviation values (closed symbols) are shown (triangle = low-flow isoflurane, circle = low flow sevoflurane, square = high-flow sevoflurane; n = 14). Note the logarithmic scale used in this graph. There was no significant difference in serum fluoride concentrations and urinary fluoride excretion between the low-flow sevoflurane and high-flow sevoflurane groups. ##P < 0.01 compared with each preoperative values. [dagger] P < 0.05, [dagger, dagger] P < 0.01 compared with the isoflurane group.