Figure 2. Heat loss was similar on the unparalyzed and on the paralyzed study day. In contrast, metabolic heat production was consistently higher on the unparalyzed study day. Systemic heat balance increased on the unparalyzed day during the anesthesia period, whereas it decreased on the paralyzed day. The first dose of interleukin-2 defined elapsed time zero; anesthesia started after 2 elapsed h and continued for 6 h. Results for the last 5 h of anesthesia are shown because peripheral tissue temperatures were unavailable during the first hour of anesthesia while needle thermocouples were being inserted. Data are presented as mean +/- SD.