Figure 5. Propofol enhancement of currents evoked by coapplication of midazolam and [small gamma, Greek]-aminobutyric acid (GABA). (A) Raw traces of propofol (0.06 to 2 [micro sign]M) potentiation of midazolam (0.06 [micro sign]M)- and GABA-evoked (1 [micro sign]M) currents. (B) Propofol potentiates GABA-evoked currents in a dose-dependent manner. The concentration of propofol that resulted in a 300% effect level, in the presence of 0.06 [micro sign]M midazolam and 1 [micro sign]M GABA, was 0.63 +/− 0.20 [micro sign]M (n = 9). The dashed line on the concentration-response curve represents the concentration of propofol that produced a 300% effect level.