Figure 5. (A) Individual serum dexmedetomidine (2.5 [micro sign]g/kg given intramuscularly) and atipamezole (intravenous doses in micrograms per kilogram are displayed) concentration-time curves in part 1 of the study (n = 6). (B) The mean serum dexmedetomidine (2.5 [micro sign]g/kg given intramuscularly; filled symbols) and atipamezole (open symbols) concentration-time curves in part 2 of the study (n = 8). Placebo (diamonds), 15 [micro sign]g/kg atipamezole (triangles), 50 [micro sign]g/kg atipamezole (circles), and 150 [micro sign]g/kg atipamezole (squares). The dotted lines indicate drug administrations.