Figure 4. Modulation of the responses to exogenous GABA by enflurane and isoflurane. (A) Response of a CA1 pyramidal cell to puff applications of GABA before, during, and after bath application of 0.6 mM enflurane. Enflurane reduced the peak amplitude of the response (a) and slowed both the rise and decay times (b). Scale bars: a = 500 pA, 400 ms; b = 200 ms. (B) The same response as show in panel A, but for a different cell responding to GABA in the absence and presence of 0.6 mM isoflurane. Scale bars: a = 1,000 pA, 400 ms; b = 200 ms.