Figure 5. The correlation between neostigmine Ce50for foot analgesia and the concentration predicted by the post hoc Bayesian individual pharmacokinetics 5 min after a bolus of 1 [micro sign]g. Similar correlations between the magnitude of the predicted concentration after a unit bolus and the Ce50for foot analgesia were seen at every time point from 1 min to 60 min after neostigmine.

Figure 5. The correlation between neostigmine Ce50for foot analgesia and the concentration predicted by the post hoc Bayesian individual pharmacokinetics 5 min after a bolus of 1 [micro sign]g. Similar correlations between the magnitude of the predicted concentration after a unit bolus and the Ce50for foot analgesia were seen at every time point from 1 min to 60 min after neostigmine.

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