Figure 7. Predicted versus measured analgesia in the hand (top panels) and foot (bottom panels), according to the population pharmacodynamic model (left panels) and the model based on the individual post hoc Bayesian estimates of the pharmacodynamics (right panels). Failure to incorporate interindividual variability in potency (left panels) reduced the accuracy of the prediction of the analgesic response. Analysis of analgesia in the hand was complicated by fairly few analgesic responses.