Figure 2. The time course of the electroencephalogram spectral edge and serum fentanyl concentrations. The spectral edge axis is inverted. The electroencephalogram spectral edge changes lag behind the changes in serum concentration. Fentanyl infusion rate = 150 [micro sign]g/kg (solid bar). Reprinted with permission. [32]

Figure 2. The time course of the electroencephalogram spectral edge and serum fentanyl concentrations. The spectral edge axis is inverted. The electroencephalogram spectral edge changes lag behind the changes in serum concentration. Fentanyl infusion rate = 150 [micro sign]g/kg (solid bar). Reprinted with permission. [32] 

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