Figure 2. Punctate hyperalgesia immediately adjacent to the incision and distant to the wound. The results are expressed as the median (horizontal line) with first and third quartiles (boxes), and tenth and nintieth percentiles (vertical lines). (A-C) Punctate hyperalgesia in sham-operated rats, after an incision to the skin and fascia or after an incision to the skin, fascia, and muscle. The sites of incision and of testing are illustrated in D. (E-G) Distant punctate hyperalgesia in sham-operated animals, after an incision to the skin and fascia or after an incision to the skin, fascia, and muscle. The sites of incision testing are illustrated in panel H. *P < 0.05 vs. pre;[dagger] P < 0.05 vs. sham.