Fig. 2. Recovery of contractile function in the left anterior descending coronary artery perfused region 180 min after final reperfusion (expressed as a percentage of the baseline value) in dogs pretreated with vehicle (VEH), or bisindolylmaleimide (2 or 8 μg/min [BIS 2 and BIS 8, respectively]) and in the presence or absence of 1 minimum alveolar concentration isoflurane (ISO). *Significantly ( P < 0.05) different from vehicle-pretreated dogs. †Significantly ( P < 0.05) different from BIS 2.