Fig. 3. Effects of halothane ( A ) and isoflurane ( B ) on 3H-dopamine (DA) release rate stimulated by N -methyl-D-aspartate (NMDA; 10−4M) in striatal slices. Experiments were performed in either the presence ( white triangles ) or absence ( white squares ) of tetrodotoxin (TTX; 5 × 10−8M). Data (mean ± SD) are expressed as a fractional increase from basal release. HAL = halothane; ISO = isoflurane. * P < 0.05, ** P < 0.01 vs. NMDA-induced release.
