American Society of Anesthesiologists

Fig. 3. Double logarithmic plot of IC50values ( table 2) and octanol–water partition coefficients ( table 1) of the nonopioids according to the Meyer–Overton rule. The IC50value for etomidate is taken from the literature. 16The regression line has a slope of −0.99 and the regression coefficient is 0.65 (n = 8). The dotted lines represent the 99% confidence interval.

Fig. 3. Double logarithmic plot of IC⁵⁰values ( table 2,) and octanol–water partition coefficients ( table 1 ) of the nonopioids according to the Meyer–Overton rule. The IC⁵⁰value for etomidate is taken from the literature. 16 The regression line has a slope of −0.99 and the regression coefficient is 0.65 (n = 8). The dotted lines represent the 99% confidence interval.

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