Fig. 3. The extent of myocardial infarction as a percentage of area at risk was similar in control (CON) dogs and those that received either a 2-min ischemic preconditioning (IPC) period alone or 1 minimum alveolar concentration (MAC) of sevoflurane (SEV) with 30 min of memory (MEM). In contrast, SEV with memory and IPC together (IPC+SEV+MEM) produced significant reductions in myocardial infarct size. *Significantly ( P < 0.05) different from CON;†Significantly ( P < 0.05) different from IPC;§Significantly ( P < 0.05) different from SEV plus MEM.