![Fig. 4. Relationship between myocardial infarct size and transmural collateral blood flow in dogs without evidence of cardioprotection ( open squares , control [CON]; open triangles , sevoflurane with memory [SEV+MEM]; open circles , 2-min period of ischemic preconditioning [IPC]) and in dogs in which sevoflurane reduced the threshold of IPC (IPC+SEV+MEM; closed circles ). The combination of IPC and sevoflurane with memory significantly ( P < 0.05) shifted the regression line ( dashed ) downward (indicating cardioprotection) in comparison to the unprotected groups ( solid line ).](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/91/5/10.1097_00000542-199911000-00037/2/37ff4.png?Expires=1716525676&Signature=aDQA2JhET1JR~I0~jO79Pf0-3VRYrDO8CpDrcZut~h2IQSiIjZW3UN9qg6emWhk1AN~HMLWz39T~5~NP5JIOzBdIGelSiD-1XS5l1Ji56noKIrkjuJCG8muAkyjQ8yXpYVqZUEm1vI94Gy0Uh0WnrECrR69UPpHh1KKNjNgVpNhnK~b2uwd-5fiuWO1AN5NRbclzhshO0IVWP3wAgiVVzidifxtykBhHri6OrQ0py97Ubfty4y1gh-hQZHORoWpJN~2tz9-t6NLXaqYtu2ZwqKVkxO4WBQtdaNooeFoU85F7ghm0rvdPWjiHTy1KfPpdOl34UeHvcdW7dQsOpcVNPQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fig. 4. Relationship between myocardial infarct size and transmural collateral blood flow in dogs without evidence of cardioprotection ( open squares , control [CON]; open triangles , sevoflurane with memory [SEV+MEM]; open circles , 2-min period of ischemic preconditioning [IPC]) and in dogs in which sevoflurane reduced the threshold of IPC (IPC+SEV+MEM; closed circles ). The combination of IPC and sevoflurane with memory significantly ( P < 0.05) shifted the regression line ( dashed ) downward (indicating cardioprotection) in comparison to the unprotected groups ( solid line ).
