Fig. 4. Neuroprotective effects of treatment with barbiturates on combined oxygen and glucose deprivation for 3 h in human NT2-N neurons. Concentrations of the barbiturates are given in micromolars. Cell death was evaluated by measuring lactate dehydrogenase release to the supernatant in percent of untreated oxygen/glucose-deprived controls 24 h after the start of the insult. *P < 0.01 versus  oxygen/glucose-deprived controls. #P < 0.05 versus  oxygen/glucose-deprived controls.