Figure 3. The effects of propofol on somatodendritic arginine vasopressin (AVP) release stimulated by glutamate. The AVP release induced by glutamate (10-3M) was inhibited by propofol at a clinically relevant concentration (10-6M). The inhibition of glutamate (10-3M)-induced AVP release by propofol was reversed by picrotoxin (10-4M). Results are expressed as a percentage increase from basal release measured for 2 min just before glutamate stimulation (mean +/- SD of 5–14 independent experiments). **Significant (P < 0.01) from the value obtained with glutamate only by one-way analysis of variance using the Scheffe F test. Intralipid had no effect on glutamate-evoked AVP release. 

Figure 3. The effects of propofol on somatodendritic arginine vasopressin (AVP) release stimulated by glutamate. The AVP release induced by glutamate (10-3M) was inhibited by propofol at a clinically relevant concentration (10-6M). The inhibition of glutamate (10-3M)-induced AVP release by propofol was reversed by picrotoxin (10-4M). Results are expressed as a percentage increase from basal release measured for 2 min just before glutamate stimulation (mean +/- SD of 5–14 independent experiments). **Significant (P < 0.01) from the value obtained with glutamate only by one-way analysis of variance using the Scheffe F test. Intralipid had no effect on glutamate-evoked AVP release. 

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