Fig. 5. Mean arterial pressure (mmHg) during the trial in patients with controlled hyperventilation (CH, closed diamond) and spontaneous breathing (SB, open diamond). Data are expressed as the mean ± SD. # and ##= differences from the corresponding reference value, at  P < 0.05 and 0.01, respectively. *  P < 0.05. **  P < 0.01. ***  P < 0.001. 

Fig. 5. Mean arterial pressure (mmHg) during the trial in patients with controlled hyperventilation (CH, closed diamond) and spontaneous breathing (SB, open diamond). Data are expressed as the mean ± SD. # and ##= differences from the corresponding reference value, at  P < 0.05 and 0.01, respectively. *  P < 0.05. **  P < 0.01. ***  P < 0.001. 

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