Fig. 1. Mean pulmonary artery pressure (mpap;± SD) of lungs in which leukocyte activation was performed with 10−6M N -formyl-Met-Leu-Phe (fMLP) in the absence or in presence of different concentrations of pancreatitis-associated protein (PAP; 260 μg/l, n = 9; 500 μg/l, n = 6). * P < 0.05 vs. fMLP, analysis of variance. PAP reduced mpap in a dose-dependent manner. Baseline values before fMLP administration at time point 0.