Table 3. Therapeutic and Nonsurrogate Outcome Measures

NNTP, NNTH, and the incidence of side effects are presented as the number of children. Duration of PACU stay and parental satisfaction scores are presented as mean ± SD. The duration of PACU stay was shorter in ondansetron 75- (P = 0.002), 100- (P = 0.001) and 150-μg/kg (P < 0.001) groups compared with the placebo group. Parents of children who received ondansetron at doses ≥75 μg/kg had a higher satisfaction compared with the placebo (P < 0.002). The parents of children who remained free of PONV had a higher satisfaction compared to those of children with PONV in the placebo and in all ondansetron groups (P < 0.01).

* n = 30 in each group.

PACU = postanesthesia care unit; PONV = postoperative nausea and vomiting.