Fig. 7. Effects of dissociative anesthetics on γ-aminobutyric acidA(GABAA) and glycine receptors. (A ) Ketamine effects on the current responses of α1β2γ2SGABAAand α1glycine receptors to EC50–60(agonist concentration giving 50–60% of the maximal response) concentrations of GABA and glycine, respectively. (n = 4). (B ) Dizocilpine effects on the current responses of α1β2γ2SGABAAand α1glycine receptors to EC50–60concentrations of GABA and glycine, respectively (n = 4).

Fig. 7. Effects of dissociative anesthetics on γ-aminobutyric acidA(GABAA) and glycine receptors. (A ) Ketamine effects on the current responses of α1β2γ2SGABAAand α1glycine receptors to EC50–60(agonist concentration giving 50–60% of the maximal response) concentrations of GABA and glycine, respectively. (n = 4). (B ) Dizocilpine effects on the current responses of α1β2γ2SGABAAand α1glycine receptors to EC50–60concentrations of GABA and glycine, respectively (n = 4).

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