Fig. 2. Experimental designs. Hypervolemic top load infusion of perflubron emulsion (A ) and acute normovolemic hemodilution with the different colloidal solutions in the presence or absence of perflubron emulsion used in the present study (B ). Wt. = weight; i.v. = intravenous; HES = hydroxyethyl starch 200/0.6; GEL = gelatin 3.5%; ALB = human serum albumin; DX-60 = dextran 60 kd 6%.