Table 3. Final 72-h Outcomes after Exsanguination and No Flow of 30 min for Each Dog

Exceptions were dogs 4, 5, and 6 of group I, which had to be terminated at 60, 52, and 42 h (see text). Dog 1 of group II was allowed to survive, was adopted, and is normal at 1 yr. Aortic flush at start of arrest was in group I with 25 ml/kg saline at 4°C (n = 6), with the tip of the balloon catheter in the thoracic aorta, and in group II with 100 ml/kg saline at 4°C (n = 7), with the tip of the balloon catheter in the abdominal aorta.

*P = 0.001. †P = 0.003. P = 0.004. § No diazepam required because anesthetized with fentanyl until final evaluation (overall performance category [OPC; 1 = normal, 5 = brain death] and neurologic deficit score [NDS; 0–100%] after fentanyl was reversed). ∥ Weakness of the hind legs (cerebral performance was normal).

Tty = lowest tympanic membrane temperature during cardiac arrest; diazepam = total dose required; HDS = total brain histologic damage score; NA = not available.