Table 1. Effect of Volatile Anesthetics on Cross-bridge Cycling Parameters

Values are means ± SD.

MAC = minimum alveolar concentration; α^fs= fraction of attached cross-bridges; k^tr= rate of force redevelopment after rapid shortening and restretching; f^app= apparent rate constant for cross-bridge attachment; g^app= apparent rate constant for cross-bridge detachment.

* Significant difference between ages (P < 0.05; n = 12 for controls, n = 6 for all other groups).

† Significant difference between control and halothane groups.

‡ Significant difference between 1 and 2 MAC anesthetic.