Fig. 2. Distribution of the maximum field rating recorded after fascial incision over the course of surgery for each patient. The field rating was recorded at 5-min intervals after administration of study drug and every 15 min thereafter until fascial closure. A field rating of 4 was assigned to one placebo patient who was classified as a treatment failure because of intraoperative events other than inadequate surgical field as described in the text. For patients who did not experience a treatment failure, the data presented correspond to the maximum field rating recorded.