Figure 3. A comparison of the rate of rise of end-tidal CO2between the high- and low-dose swine following the initiation of episodes of malignant hyperthermia. The low-dose animals were triggered with halothane (0.87%) and succinylcholine (2 mg/kg), whereas the high-dose animals triggered with or during 4-chloro-m-cresol infusions at cumulative doses greater than 17.04 mg/kg (1,500 [micro sign]mol). End-tidal CO2was normalized to 70 mmHg at time 0. Values represent means +/- SD.