Fig. 4. Responses to (A ) thermal and (B ) mechanical stimulation. Latencies are shown as mean ± SEM and mechanical thresholds as medians, quartiles, and 10th and 90th percentiles. Basal responses were measured before (open bars) and carrageenan responses 3.5 and 4.0 h after (dark bars) intraplantar injection of the irritant. The intrathecal injection (saline or 5 μg Joro spider toxin [JST]) was given 30 min after carrageenan (*statistical difference [P ≤ 0.05] between the two treatment groups).