Fig. 8. Effects of F3 and F6 on Na+channel steady state inactivation. Na+currents were elicited by test pulses to −10 mV after 500-ms prepulses to potentials varying from −150 to −10 mV. Representative peak currents were normalized and plotted as a function of prepulse potential. F3 shifted inactivation by −21 mV at 0.6 mM (n = 4); F6 caused a shift of −3.2 mV at 0.07 mM (n = 5).