Fig. 3. Time course of phasic (systolic–diastolic [sys-dia]) [Ca2+] (A ) and systolic–diastolic left ventricular pressure (LVP) (B ) before, during, and after global ischemia in CON, SBI, SBAI, and SAI groups. Note that systolic–diastolic [Ca2+] decreased during ischemia in all groups and increased approximately twofold during initial reperfusion in the CON group, but that the increase was smaller in each sevoflurane (SEV) group. Phasic LVP was higher in each sevoflurane group on reperfusion and was especially higher in the SBI and SBAI groups up to 60 min of reperfusion. See figure 1for details on groups and statistics.