Fig. 1. Isoflurane minimum alveolar concentration (MAC) decreases by increasing the concentration of a cyclic guanosine monophosphate (cGMP)–dependent protein kinases Iα inhibitor, Rp-8-p-CPT-cGMPS. Data are presented as the mean ± SEM. n = 8 animals for each dose, except n = 7 for the 200 μg Rp-8-p-CPT-cGMPS. *P < 0.05 versus  control; **P < 0.01 versus  control; †P < 0.05 versus  preceding concentration.

Fig. 1. Isoflurane minimum alveolar concentration (MAC) decreases by increasing the concentration of a cyclic guanosine monophosphate (cGMP)–dependent protein kinases Iα inhibitor, Rp-8-p-CPT-cGMPS. Data are presented as the mean ± SEM. n = 8 animals for each dose, except n = 7 for the 200 μg Rp-8-p-CPT-cGMPS. *P < 0.05 versus  control; **P < 0.01 versus  control; †P < 0.05 versus  preceding concentration.

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