Fig. 1. Ischemic preconditioning reduces hippocampal CA1 neuronal damage in a rat forebrain ischemia model. Neuronal survival was examined 7 days after reperfusion by neuro-nuclear specific protein immunostaining. Bar = 100 μm. (A ) Sham operation; (B ) 3-min ischemia; (C ) 8-min ischemia plus sham operation; (D ) 8-min ischemia with preconditioning.