![Fig. 1. Halothane-induced, dose-dependent increase of [Ca2+]iin cultured skeletal muscle cells from six malignant hyperthermia–susceptible (MHS) individuals (n = 42; solid dots and line) and four control individuals (n = 32; open dots and dotted line). Discrimination between MHS and control is 100% beyond 0.5 mm halothane (P < 0.05). (Inset ) [Ca2+]iresponse at clinically used halothane concentrations (< 1.0 mm).](https://asa2.silverchair-cdn.com/asa2/content_public/journal/anesthesiology/97/1/10.1097_00000542-200207000-00038/2/38ff1.png?Expires=1716963112&Signature=hNPVJpGLsEydaIsqIRyF57A1yD2jICtqKrwLQh1WwKqairiQJiX7wkv2on0ssWbsmuLtoIXipo0TERWEfdlaIuuMQlASNF8Vf8T9~pz4b0M9FXG9JzSHTqONQf3zAJCwwV~jEArxAfHR22tgonl1WbzfVKD5EkwibhAuJBHygPCB9V9ne2gxGI~Qm41tNQ8tdT2PhP1WpcKT4To-o-Rt9QUvm3VJfeBwcMg1bj2pepoWce3mrwA81FEZM-0de~DrxCFSZLmCJGKuDdBHBBPcal5UAP8v9ibX14cwe-uTla1vMK75nf4XRXkMqMcVXORCSG9U908y2joKdbNl2gr1gg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Fig. 1. Halothane-induced, dose-dependent increase of [Ca2+]iin cultured skeletal muscle cells from six malignant hyperthermia–susceptible (MHS) individuals (n = 42; solid dots and line) and four control individuals (n = 32; open dots and dotted line). Discrimination between MHS and control is 100% beyond 0.5 mm halothane (P < 0.05). (Inset ) [Ca2+]iresponse at clinically used halothane concentrations (< 1.0 mm).
