Fig. 3. Effects of soluble factors and cellular components separated from stored whole blood on lipopolysaccharide-stimulated cytokine response. Stored allogeneic whole blood of a donor was separated into soluble and cellular factors by centrifugation. Each fraction was coincubated with equal amounts of fresh blood of a recipient (n = 5). Box plots represent the 25th/75th percentile, median and range. *P < 0.05 as compared with controls corrected for dilution; #P < 0.05 between soluble and cellular fraction. IL = interleukin; LPS = lipopolysaccharide; TNF = tumor necrosis factor.