Fig. 4. Comparison of contracture test and acidification assay. (A ) Contracture force in the in vitro contracture test (IVCT) plotted versus 4-chloro-m-cresol (4-CmC) concentration. Results from 13 of 16 biopsies (7 malignant hyperthermia–susceptible [MHS], 6 malignant hyperthermia–normal [MHN]) that were used for the myotube cultures. Error bars indicate SD. (B ) Correlation between IVCT data and Cytosensor®(