Fig. 2. Competitive displacement of 3H-QNB by cisatracurium in membranes prepared from Chinese hamster ovary cells expressing the M2 or M3 muscarinic receptor. Cisatracurium has a higher affinity for the M2 versus  the M3 muscarinic receptor. However, the 50% inhibitory concentration value for the M2 muscarinic receptor falls to the far right of reported plasma concentrations. (n = 3 for M2 and M3, respectively.)

Fig. 2. Competitive displacement of 3H-QNB by cisatracurium in membranes prepared from Chinese hamster ovary cells expressing the M2 or M3 muscarinic receptor. Cisatracurium has a higher affinity for the M2 versus  the M3 muscarinic receptor. However, the 50% inhibitory concentration value for the M2 muscarinic receptor falls to the far right of reported plasma concentrations. (n = 3 for M2 and M3, respectively.)

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