Fig. 1. Dose-dependent protection by sevoflurane (SEVO) and isoflurane (ISO) in myocytes exposed to 60 or 120 min of ischemia. The number of myocytes stained with trypan blue is indicated as percentage of total viable myocytes before ischemia. Data are mean ± SD. MAC = minimum alveolar concentration; CTL = control group. *P < 0.001, any bar of SEVO- or ISO-treated myocytes versus the respective CTL bar or the respec-tive bar at the preceding lower MAC value. #P not significant, bar of SEVO- or ISO-treated myocytes at 2.0 MAC versus the respective bar at 1.5 MAC.