Fig. 6. Effect of adenosine and guanosine triphosphate (GTP) on the KATPchannel. Single-channel current traces were monitored in the inside-out patch mode. The effect of GTP (200 μm) in the absence (A ) and presence (B ) of adenosine in the pipette solution is shown. The arrows indicate zero current level. (C ) Summarized data for the isoflurane effect on KATPchannel open probability in the presence of adenosine and GTP. *P < 0.05 versus control group, n = 5.