Table 4. Pharmacokinetic–Pharmacodynamic Fitting Results for the Sheiner Model

Molecular-weight rocuronium = 609.69. Values are shown as median with range in parentheses.

γ= steepness of concentration–effect relation; EC⁵⁰= rocuronium concentration at 50% effect, molecular weight rocuronium = 609.69; k^e0= rate constant between plasma and effect compartment.